Purine and pyrimidine nucleotides play crucial roles in major cell functions: they are the basic building blocks of nucleic acids, are the components of key cell metabolic processes such as energy metabolism, or the biosynthesis of phospholipids and glycoproteins and are involved in cell signaling mechanisms. Quantification of nucleotides is therefore of great interest in cell biology research as well as for many industrial application fields, such as pharmacology, drug discovery or foodstuffs QC.
NOVOCIB is a French biotechnology company which has specialized and developed a strong expertise in the study of nucleotides metabolism and the analysis of nucleosides and nucleotides.
NOVOCIB's commitment was born in 2003 of a research program against Hepatitis C Virus (HCV) for the discovery of new antiviral drugs, especially nucleoside analogues.
This chalenging project was awarded with three National prestigious prizes (to know more, please visit Company section) and led NOVOCIB to implement PRECICE®, its proprietary bio-analytical platform, and to develop a unique and still growing range of analytical tools, enzymatic assays and diagnostic systems specially designed for the analysis of nucleotides and related applications.
NOVOCIB products and services are specifically designed for:
| Drug Discovery / Life Science |
| • Recombinant enzymes of nucleotide metabolism • In vitro screening on validated targets ; kinetics studies (IC50) • Pharmacology of Nucleoside Analogues • Nucleotide Analysis of biological samples • Medicinal Chemistry: enzymatic tools for Nucleoside Analogue synthesis (trans-ribosylation) • COMING SOON: Ultrasensitive Enzymatic Kit for Phosphate detection |
| Food QC Assays & Kits |
| • Nucleotide analysis of baby milk • Fish & Seafood freshness: K-value measurement by analytical method • COMING SOON: Enzymatic Kit for K-value measurement |
